A dynamic gradient ratio test apparatus

Experimental and Computational Study on Hydrodynamic of a Downscaled Mini Vessel USP Dissolution Test Apparatus II

Although not listed on the United States Pharmacopeia (USP), like standard USP 2, small volume USP 2 dissolution apparatus has gained a great deal of attention, especially for cases where small amount of drug product is available for testing in research and design step or evaluations are to be made on a tablet containing trace amounts of the active pharmaceutical ingredient. In this work, first...

Dynamic venous access pressure ratio test for hemodialysis access monitoring.

BACKGROUND Early recognition of arteriovenous graft (AVG) dysfunction in hemodialysis (HD) patients followed by prompt corrective procedures reduces AVG thrombosis rates and lengthens access survival. We developed a method to prospectively monitor AVGs that uses an algorithm to calculate venous access pressure (VAP) during HD from the venous drip chamber pressure (VDP). METHODS Sham HD with b...

Rayleigh Test Apparatus Design Report

Likelihood Ratio Gradient Estimationfor Stochastic

In this paper, we develop mathematical machinery for verifying that a broad class of general state space Markov chains reacts smoothly to certain types of perturbations in the underlying transition structure. Our main result provides conditions under which the stationary probability measure of an ergodic Harris recurrent Markov chain is diierentiable in a certain strong sense. The approach is b...

A likelihood ratio test for idiosyncratic unit roots in a dynamic-factor model with integrated factors

We consider an exact factor model with the restriction of unobservable common stochastic trends imposed by non-stationary factors as considered by Zhou and Solberger (2012). Conditional on this, we propose a homogenous likelihood ratio test for unit roots in the idiosyncratic components. The likelihood approach has long been overlooked in this framework due to numerical burdens, and though part...